International Journal of Medical and Surgical Sciences 2024-04-01T00:00:00+00:00 Dr. Iván Suazo Open Journal Systems <p><strong>International Journal of Medical and Surgical Sciences</strong>, (IJMSS) is a serial and peer-review publication, ascribed by the Faculty of Health Sciences and administered by the Vice-Rector's Office for Research and Postgraduate Studies of the Universidad Autónoma de Chile. IJMSS has an international scope, is open access and uses a License Creative Commons of Recognition -Non-Commercial-without derivatives 4.0 International (CC BY-NC-ND 4.0). The contents are available in open access immediately after being published.</p> <p><strong>Objective</strong>: To publish original research papers within the medical and surgical sciences, on all basic scientific aspects of structure, chemistry, developmental biology, physiology and pathology of relevant tissues, microbiology, biomaterials, and behavioral sciences. In general, analytical studies are preferred to descriptive ones.</p> <p><strong>Vision</strong>: IJMSS seeks to be a space for academic discussion and multidisciplinary dialogue in the area of biomedical, medical and surgical sciences in all its aspects, which contributes to scientific communication between research peers and academics in the area.</p> <p><strong>Aimed to</strong> professionals and academics in the field of medical and surgical sciences, health administration, and related specialties.</p> <p>The Journal Publishes in continuous publication schema (four issues per year), original articles, reviews, short communications and letters to the editor in English and Spanish. The IJMSS has <strong>no article processing charges (APC)</strong> or article submission charges for any of the editorial processes or publication.</p> <p><strong>e-ISSN</strong> 0719-532X</p> <p><strong>p-ISSN</strong> 0719-3904</p> Evaluation of wheat (Triticum aestivium L) diet on reproductive functions of adult female rats 2024-01-30T09:16:43+00:00 Chika Anna Idaguko Gladys Agoreyo <p>Introduction: The relationships between wheat diet, sex hormone and the estrous cycle are important from the perspective of fertility. Aim: This study aims to investigate the effect of wheat diet on weight, estrous cycle, reproductive hormones and histology of the ovary of female Sprague-Dawley rats. Methods: Prior to the test, vaginal smear was monitored daily for 16 days period to select females with normal (regular) estrous cycle. A total of twenty rats with regular estrous cycle weighing between 170-200 g were randomized into four sets of 5 animals each. Group A is the female control and was fed with rat chow, group B, C and D was given 40%, 60%, 100% of wheat diet respectively. The wheat diet was giving respectively for a period of 4 weeks. Estrous cycle pattern was monitored using the vaginal smear for 16 days. At the end of the experiment, the rats were sacrificed and the blood sample were taken for follicle stimulating hormone, luteinizing hormones, estradiol, and progesterone analysis. The histology of the ovary were carried out. Results: The result showed that there was an increase in the weight of the rats that was fed with wheat and the increase was diet dependent. The wheat diets disrupt the order of appearance of normal estrous cycle stages, hence; there was no constancy in the frequency of all cycle stages in the wheat groups, mostly the 100% wheat group. No significant endocrine or histological differences noticed between control and wheat diets groups. Therefore photomicrograph of wheat diet shows large corpus luteum, thick germinal epithelium, zona granulosa and oocyte. Conclusion: Wheat diets disrupt the estrous cycle of the rats; however no adverse effect was noticed on the circulating reproductive hormones and histology of the ovary. However, high consumption of wheat should be taken with precaution.</p> 2024-04-10T00:00:00+00:00 Copyright (c) 2024 Chika Anna Idaguko, Gladys Agoreyo Telemedicine from the perspective of health personnel in a public hospital in Paraguay, 2023Telemedicine from the perspective of health personnel in a public hospital in Paraguay, 2023 2024-01-04T19:39:04+00:00 Chap Kau Kwan Chung Carlos Rafael Riquelme Benítez <p>The study investigates the adoption of telemedicine in a public hospital in Paraguay in 2023, from the perspective of healthcare personnel. A quantitative, descriptive, and cross-sectional analysis was conducted through 23 interviews with healthcare staff who were selected based on their voluntary participation, excluding maintenance, administration, finance, and cleaning staff. An 11-question guide focused on the evaluation, implementation, usage, and economic, technological, and legal aspects of telemedicine was used. Key findings highlight the feasibility of telemedicine, its more frequent application in the private sector, and benefits such as ease of access, resource optimization, and time management. The security of medical information emerged as a paramount concern. The conclusion is that there is a positive acceptance of telemedicine among professionals, underscoring the need for institutional, governmental, and user support for its effective implementation.</p> 2024-04-01T00:00:00+00:00 Copyright (c) 2024 Chap Kau Kwan Chung, Rafael Riquelme Benítez Clinical characteristics and response to therapeutic plasma exchange in patients diagnosed with Guillain Barré syndrome in a third level clinic in the city of Cali - Colombia during the years 2016-2022. 2024-01-23T05:54:28+00:00 Diego Gerardo Prado Molina Esteban Agudelo-Quintero José Mauricio Cárdenas-Prieto Juan Santiago Serna Trejos Stefanya Geraldine Bermúdez – Moyano Isabella Vernaza-Gutiérrez Luis Felipe Cortez-Sanabria Catherine Caceres-Campo Abstract Introduction: Guillain Barré syndrome (GBS) presents a non-negligible incidence rate in low-income countries. Intravenous human immunoglobulin (IVIG) and therapeutic plasma exchange (TPR) are the first-line treatments. Aim: The aim of this work is to describe the clinical characteristics and the response to RPT in patients with GBS. Materials and methods: Observational, descriptive, cross-sectional study with analytical scope of patients diagnosed with GBS who were managed with RPT, in two service-providing institutions (IPS) in the city of Cali-Colombia, between 2016 and 2022. outcomes: 33 patients with a mean age of 57+/-16 years were included. After a median stay of 10 days in the intensive care unit (ICU), 75.5% decreased at least one grade on the Hughes scale, 12.1% required mechanical ventilation (MV), 27.3% presented some complication, and there were no fatal outcomes. Prolonged stay in the ICU was significantly associated with an unfavorable clinical evolution. Conclusion: The results suggest that RPT management in an institution with highly complex standards, with early diagnosis and early medical intervention, can contribute to an adequate clinical evolution. Prolonged time in the intensive care unit (ICU) is a prognostic factor to consider in the clinical evolution of these patients. Studies with an analytical design and a larger sample are required to support these findings. Keywords Guillain-Barré syndrome, plasma exchange, clinical evolution, intravenous immunoglobulin, early diagnosis, early medical intervention. 2024-04-01T00:00:00+00:00 Copyright (c) 2024 Diego Gerardo Prado- Molina , Esteban Agudelo-Quintero, José Mauricio Cárdenas-Prieto, Juan Santiago Serna Trejos, Stefanya Geraldine Bermúdez – Moyano, Isabella Vernaza-Gutiérrez, Luis Felipe Cortez-Sanabria, Catherine Caceres-Campo Global overview of monkeypox: An epidemiological and clinical update 2023-11-22T02:49:55+00:00 Diego Gerardo Prado Molina Juan Santiago Serna Trejos Stefanya Geraldine Bermúdez Moyano Esteban Agudelo-Quintero Juan Pablo Rojas-Hernández <p>Mpox (viruela símica) es una enfermedad viral que puede producir síntomas como erupción cutánea, adenomegalias y fiebre. Pese a su baja tasa de mortalidad, se relaciona con complicaciones que pueden comprometer la calidad de vida de las personas. Fue identificada por primera vez en humanos en 1970, desde entonces se mantenía una distribución geográfica y una incidencia controladas. No obstante, desde el año 2022 su incidencia ha aumentado al igual que su distribución geográfica alcanzando un total de 89.596 casos confirmados por laboratorio y 663 casos probables, incluidas 157 muertes, reportados al 28 de agosto de 2023; llegando incluso a países no endémicos. A continuación, se presenta una revisión narrativa con base en información recolectada en bases de datos como UpToDate, Google Scholar, Medline, ClinicalKey, Scopus, Embase, Pubmed; con el objetivo de describir los aspectos más relevantes de Mpox en humanos desde una perspectiva epidemiológica actual, además de presentar datos fisiopatológicos, de diagnóstico, tratamiento, pronóstico y rehabilitación.</p> 2024-04-01T00:00:00+00:00 Copyright (c) 2024 Diego Gerardo Prado-Molina, Juan Santiago Serna Trejos, Stefanya Geraldine Bermúdez–Moyano, Esteban Agudelo-Quintero , Juan Pablo Rojas-Hernández