International Journal of Medical and Surgical Sciences
https://revistas.uautonoma.cl/index.php/ijmss
<p><strong>International Journal of Medical and Surgical Sciences</strong>, (IJMSS) is a serial and peer-review publication, edited by the Universidad Autónoma de Chile. IJMSS has an international scope, is open access and uses a License Creative Commons of Recognition -Non-Commercial-without derivatives 4.0 International (CC BY-NC-ND 4.0). The contents are available in open access immediately after being published.</p> <p><strong>Objective</strong>: To publish original research papers within the medical and surgical sciences, on all basic scientific aspects of structure, chemistry, developmental biology, physiology and pathology of relevant tissues, microbiology, biomaterials, and behavioral sciences. In general, analytical studies are preferred to descriptive ones.</p> <p><strong>Vision</strong>: IJMSS seeks to be a space for academic discussion and multidisciplinary dialogue in the area of biomedical, medical and surgical sciences in all its aspects, which contributes to scientific communication between research peers and academics in the area.</p> <p><strong>Aimed to</strong> professionals and academics in the field of medical and surgical sciences, health administration, and related specialties.</p> <p>The Journal Publishes in continuous publication schema (four issues per year), original articles, reviews, short communications and letters to the editor in English and Spanish. The IJMSS <strong>has no article processing charges (APC)</strong> or article submission charges for any of the editorial processes or publication.</p> <p><strong>e-ISSN</strong> 0719-532X</p> <p><strong>p-ISSN</strong> 0719-3904</p>Universidad Autónoma de Chileen-USInternational Journal of Medical and Surgical Sciences0719-3904<p>The publication is free and its contents are distributed under <a href="https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en">Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). </a>The rights of the works published in this journal are property of the author and they are free to distribute and disseminate the same sources as long as he correctly cites the font of publication, these acts are not for commercial purposes and no derivative works are generated.</p>From Anatomy to Algorithm: Scope of AI-Assisted Diagnostic Competencies in Health Sciences Education
https://revistas.uautonoma.cl/index.php/ijmss/article/view/2818
The article explores the evolution of medical knowledge from its anatomical and functional foundations to the integration of advanced technological tools, focusing on the impact of artificial intelligence (AI) on the development of diagnostic competencies. Initially, medical training relied on direct observation and clinical judgment based on anatomical and surgical knowledge. Subsequently, the inclusion of physiology and pathology enabled a functional understanding of the human body, transforming diagnosis into a systematic skill supported by objective data such as laboratory tests and medical imaging. The integration of AI in recent decades has revolutionized this process, offering unprecedented capabilities to analyze complex clinical data. Tools such as machine learning algorithms and predictive systems have enhanced diagnostic precision, allowing for the identification of previously unnoticed patterns. This data-driven approach strengthens physicians’ ability to correlate clinical symptoms and signs with specific pathological entities. However, the incorporation of AI presents challenges in medical education. Future physicians must combine learning traditional clinical foundations with mastering advanced technologies, all while maintaining an ethical and patient-centered approach. Furthermore, excessive reliance on technology and biases inherent in algorithms underscore the need to balance technological innovation with human clinical judgment. The article highlights that medical education must adapt to include critical competencies such as digital literacy, ethical reasoning, and critical thinking. AI-based simulators and educational platforms are playing a key role in preparing physicians for a more digitized clinical environment, while research remains essential to ensure transparency and fairness in these technologies. Iván Suazo Galdames
Copyright (c) 2024 Iván Suazo Galdames
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2024-11-212024-11-2111312410.32457/ijmss.v11i3.2818Subjective and objective evaluation of nasal obstruction in patients treated at the Hospital de Clínicas, Paraguay
https://revistas.uautonoma.cl/index.php/ijmss/article/view/2633
<p>Nasal obstruction is characterized by insufficient airflow and increased resistance in the nasal cavities, affecting patients’ quality of life and sleep. This study aims to compare the efficacy of medical and surgical treatment in patients with Nasal obstruction, using subjective evaluations (NOSE and VAS scales) and objective evaluations (active anterior rhinomanometry). This is an experimental and prospective longitudinal study conducted at the Hospital de Clínicas, Paraguay. Forty patients with Nasal obstruction were included, divided into medical treatment (nasal corticosteroids) and surgical treatment (turbinoplasty, septoplasty, or both) groups. Pre- and post-treatment evaluations were performed using the NOSE and VAS scales, and active anterior rhinomanometry. The sample included 52.5% men and 47.5% women, with an average age of 32.18±11.59 years. The main cause of Nasal obstruction was chronic rhinitis (62.5%). Treatments showed significant improvements in subjective and objective evaluations. In the medical group, VAS improved by 2.63 points in women and 2.00 in men, while the surgical group showed more pronounced improvements. The NOSE also showed significant reductions, especially in patients undergoing combined turbinoplasty and septoplasty. Active anterior rhinomanometry reflected an increase in overall nasal flow in all treated groups. Both medical and surgical treatments are effective in improving Nasal obstruction, with greater benefits observed in surgical treatments. Subjective and objective evaluations are valuable and complementary tools for assessing treatment in patients with Nasal obstruction. These results highlight the importance of a comprehensive evaluation in the management of Nasal obstruction.</p>Rodrigo David González InsfránAna Alicia María BenítezCarlos Mena CanataEnrique Pérez Julio Heinichen
Copyright (c) 2024 Rodrigo David González Insfrán, Ana Alicia María Benítez, Carlos Mena Canata, Enrique Pérez, Julio Heinichen
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2024-09-272024-09-2711311310.32457/ijmss.v11i3.2633Effect of Orijin Bitters, Aqueous Extracts of Hibiscus Sabdariffa and Zingiber Officinale Roscoe on the Kidney of Adult Wistar Rats
https://revistas.uautonoma.cl/index.php/ijmss/article/view/2777
<p class="p1">Orijin bitters, Hibiscus sabdariffa and <span class="s1">Zingiber officinale roscoe </span>have been reported to possess various medicinal properties. The aim of the study is to evaluate their effects on the kidney of adult wistar rats. Methodology<span class="s1">: </span>thirty rats were randomly divided into 6 groups, each having 5 rats. Group 1 received distilled water, group 2, 70cl/70kg/bw orijin bitters, group 3, orijin bitters and 200mg/kg/bw Hibiscus sabdariffa calyx aqueous extract, group 4, orijin bitters and 500mg/kg/bw Hibiscus sabdariffa calyx aqueous extract, group 5, orijin bitters and 200mg/kg/bw <span class="s1">officinale </span>rhizome aqueous extract, group 6, orijin bitters and 500mg/kg/bw <span class="s1">Zingiber officinale </span>rhizome aqueous extract over a 21- day period. After administration, the rats were sacrificed and the kidney harvested for biochemical and histological analysis. Results: Orijin bitters altered renal function, indicated by elevated level of malondialdehyde and decreased level of superoxide dismutase, catalase and glutathione, along with histopathological changes such as glomerular atrophy and tubular degeneration compared to the control. The result was not statistically significant (P < 0.05). Conversely, aqueous <span class="s2">extracts of </span>Hibiscus sabdariffa <span class="s2">calyx and </span>Zingiber officinale <span class="s2">rhizome exhibited </span>antioxidant properties, reducing oxidative stress and mitigating renal damage compared to the orijin bitters group only. Although the result was not statistically significant (P < 0.05). Conclusion: Orijin bitters may have nephrotoxic effects, <span class="s2">while </span>Hibiscus sabdariffa <span class="s2">and </span>Zingiber officinale may offer protective benefits, due to their antioxidant properties.</p>Sarah I. DavidGodfrey DuruAbigail Abraham Samuel Victor Ita
Copyright (c) 2024 Sarah I. David, Godfrey Duru, Abigail Abraham, Samuel Victor Ita
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2024-11-222024-11-2211311610.32457/ijmss.v11i3.2777Chronic granulomatous intestinal disease: case report
https://revistas.uautonoma.cl/index.php/ijmss/article/view/2557
<p>Chronic intestinal granulomatous disease is a disorder that directly compromises the entire immune system. The estimated incidence is one in a million inhabitants. Among the associated risk factors, the presence of chronic and recurrent infections stands out. In the present case, it is a 39-year-old female patient with a history of intestinal obstruction and endometriosis, who presents abdominal pain in the left abdomen and recurrent abdominal pain without an identifiable cause. Laboratory tests revealed leukocytosis and mild neutrophilia. The tomography showed intestinal dilation at the jejunoileal level without transition zones, and the serological tests were negative. Exploratory laparoscopy was performed and the presence of tumor implants was found in the omentum, extending to the abdominal, uterine, intestinal, and peritoneal regions, as well as sallow fluid at the abdominal level. Tumor markers are normal. Histopathology details fungal colonization with eosinophilic necrosis and presence of granulomas, negative immunohistochemistry for Aspergillus and negative Lowestein-jensen culture. Antifungal and antituberculous treatment was started, with a decrease in symptoms and improvement in the clinical picture.</p>Jesús Nicolás Larco Coloma Byron Salgado Lomas Nathalie Estephania Pungacho EspinNicolas Larco NoboaLizbeth Doménica Mayorga Buenaño
Copyright (c) 2024 Jesús Larco, Nicolás Larco, Byron Salgado, Nathalie Pungacho, Lizbeth Mayorga
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2024-09-242024-09-241131710.32457/ijmss.v11i3.2557Syncope as a clinical presentation of cardiac lymphoma: a case report
https://revistas.uautonoma.cl/index.php/ijmss/article/view/2603
<p>Primary cardiac lymphoma, an extremely rare type of B-cell non-Hodgkin lymphoma, has an incidence of approximately 0.02-2% among malignant cardiac tumors. It is frequently associated with manifestations such as cardiac rhythm disturbances, refractory pericardial effusion and cardiac masses. Definitive diagnosis is achieved by biopsy, being essential to rule out hematogenous dissemination with PET-CT. The literature indicates a predominance of right chamber involvement and survival that varies significantly according to left ventricular involvement and the presence of arrhythmias. Therapeutic options are not well defined, but chemotherapy such as R-CHOP has shown efficacy, although the prognosis is generally poor due to complications such as disease progression, arrhythmias and sepsis. This case underscores the importance of considering cardiac lymphoma in patients with unexplained cardiac symptoms, highlighting the need for a multidisciplinary and specific diagnostic and therapeutic approach.</p>Juan Santiago Serna TrejosCarlos Andrés Castro – GalvisStefanya Geraldine Bermúdez – MoyanoLaura Catalina Rodríguez – FonsecaJaqueline Paola Tipas – CuespudIsabella Caicedo – OrtizJuan David López – Ponce de León
Copyright (c) 2024 Juan Santiago Serna–Trejos, Carlos Andrés Castro–Galvis, Stefanya Geraldine Bermúdez–Moyano, Laura Catalina Rodríguez–Fonseca, Jaqueline Paola Tipas–Cuespud, Isabella Caicedo–Ortiz, Juan David López–Ponce de León
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2024-10-112024-10-1111311010.32457/ijmss.v11i3.2603