International Journal of Medical and Surgical Sciences https://revistas.uautonoma.cl/index.php/ijmss <p><strong>International Journal of Medical and Surgical Sciences</strong>, (IJMSS) is a serial and peer-review publication, edited by the Universidad Autónoma de Chile. IJMSS has an international scope, is open access and uses a License Creative Commons 4.0 International (CC BY 4.0). The contents are available in open access immediately after being published.</p> <p><strong>Objective</strong>: To publish original research papers within the medical and surgical sciences, on all basic scientific aspects of structure, chemistry, developmental biology, physiology and pathology of relevant tissues, microbiology, biomaterials, and behavioral sciences. In general, analytical studies are preferred to descriptive ones.</p> <p><strong>Vision</strong>: IJMSS seeks to be a space for academic discussion and multidisciplinary dialogue in the area of biomedical, medical and surgical sciences in all its aspects, which contributes to scientific communication between research peers and academics in the area.</p> <p><strong>Aimed to</strong> professionals and academics in the field of medical and surgical sciences, health administration, and related specialties.</p> <p>The Journal Publishes in continuous publication schema (four issues per year), original articles, reviews, short communications and letters to the editor in English and Spanish. The IJMSS <strong>has no article processing charges (APC)</strong> or article submission charges for any of the editorial processes or publication.</p> <p><strong>e-ISSN</strong> 0719-532X</p> <p><strong>p-ISSN</strong> 0719-3904</p> en-US <p>La publicación se distribuye bajo la <a href="https://creativecommons.org/licenses/by/4.0/">Licencia <em>Creative Commons</em> Atribución- 4.0 Internacional</a> (<a href="https://creativecommons.org/licenses/by/4.0/">CC BY 4.0</a>). Los derechos de los trabajos publicados en esta revista son propiedad del autor, los cuales son libres de distribuir y difundir las mismas, siempre que cite correctamente la fuente.</p> ijmss@uautonoma.cl (Dr. Iván Suazo) editorjournal@uautonoma.cl (Andrea Rubilar Urra) Fri, 17 Jan 2025 00:00:00 +0000 OJS 3.3.0.10 http://blogs.law.harvard.edu/tech/rss 60 Reel’s syndrome, an unusual cause of lead displacement https://revistas.uautonoma.cl/index.php/ijmss/article/view/2773 <p>Background: Ventricular capture failure could be a sign of macrodisplacement. Electrode displacement is one of the complications related to cardiac pacing. Knowing the different production mechanisms of macrodisplacements is not just for a nominal distinction. It is important to understand that the mechanisms are different, that´s why each type of macrodisplacement requires different form of therapy. Case report: A 79-year-old male patient. On physical examination, the heart rate was 38 beats per minute. The 12-lead electrocardiogram (ECG-12) showed a second-degree 2:1 atrioventricular block. It was decided to implant a VVIR pacemaker. On follow-up, the ECG-12 review showed ventricular capture failure without spike and 2:1 atrioventricular block. The fluoroscopic study showed electrode displacement. The distal tip of the electrode was in the area of the pacemaker pocket with radiological appearance of thread wound on a reel. Reintervention was immediately decided, during surgery, the diagnosis of reel type macrodisplacement was corroborated. The lead was repositioned in the right ventricle. Conclusions: Knowledge of the risk factors allows us to avoid macrodisplacement syndromes of the electrode. Knowing the different mechanisms of production of the three syndromes described is of great importance to finally carry out the appropriate therapy.</p> Armando E. Hernández Castellón, Fernando Rodríguez González, Juan Miguel Cruz Elizundia, Elibet Chávez-González Copyright (c) 2025 Armando E. Hernández Castellón, Fernando Rodríguez González, Juan Miguel Cruz Elizundia, Elibet Chávez-González https://creativecommons.org/licenses/by/4.0 https://revistas.uautonoma.cl/index.php/ijmss/article/view/2773 Tue, 25 Feb 2025 00:00:00 +0000 Therapeutic revolution in the management of metastatic prostate cancer https://revistas.uautonoma.cl/index.php/ijmss/article/view/3001 <p>not applicable</p> Aracelli Barría-Alfaro, Javiera Gajardo-Von Kunowsky, Andrés Vega-Avalos, Francisco Vidangossy Copyright (c) 2025 Aracelli Barría-Alfaro, Javiera Gajardo-Von Kunowsky, Andrés Vega-Avalos, Francisco Vidangossy https://creativecommons.org/licenses/by/4.0 https://revistas.uautonoma.cl/index.php/ijmss/article/view/3001 Fri, 06 Jun 2025 00:00:00 +0000 Cancer research in Chile: beyond universities, contributions from The National Cancer Institute https://revistas.uautonoma.cl/index.php/ijmss/article/view/2997 Ximena González, Berta Cerda, Ana María Ciudad, Isabel Abarca, Diego Rojas, Rossana Guerrero, Carmen Gloria San Martín, Juvenal A. Ríos Leal Copyright (c) 2025 Juvenal A. Ríos Leal, MD, PhD, Ximena González, Berta Cerda, Ana María Ciudad, Isabel Abarca, Diego Rojas, Rossana Guerrero, Carmen Gloria San Martin https://creativecommons.org/licenses/by/4.0 https://revistas.uautonoma.cl/index.php/ijmss/article/view/2997 Wed, 02 Apr 2025 00:00:00 +0000 Clinical utility of point-of-care ultrasonography in the patient on shock: A narrative review https://revistas.uautonoma.cl/index.php/ijmss/article/view/2792 <p>Shock, a medical emergency characterized by inadequate perfusion and organ dysfunction, can be classified as distributive, hypovolemic, cardiogenic and obstructive. Point-of-care ultrasound (POCUS) has established itself as a fundamental tool in the differential diagnosis and therapeutic guidance in patients with shock. This article reviews the clinical utility of POCUS, highlighting its high diagnostic accuracy in differentiating types of shock, with sensitivities and specificities greater than 90% in scenarios such as hypovolemic and obstructive shock. In addition, the use of POCUS has been shown to improve diagnostic accuracy in the emergency department, optimize hydric resuscitation and reduce mortality in critical patients. Its implementation strengthens clinical decision making, integrating a rapid and effective diagnostic approach that favors interdisciplinary management to prevent multiorgan failure and death.</p> Juan Santiago Serna - Trejos, Stefanya Geraldine Bermúdez – Moyano, Manuela Castaño – Orozco, Vanessa Montoya – Valencia, Juan Camilo Diaz – Beltrán, Melissa Martínez – Garcia, Henry Fernando Botero – Suárez Copyright (c) 2025 Juan Santiago Serna - Trejos, Stefanya Geraldine Bermúdez – Moyano, Manuela Castaño – Orozco, Vanessa Montoya – Valencia, Juan Camilo Diaz – Beltrán, Melissa Martínez – Garcia, Henry Fernando Botero – Suárez https://creativecommons.org/licenses/by/4.0 https://revistas.uautonoma.cl/index.php/ijmss/article/view/2792 Fri, 17 Jan 2025 00:00:00 +0000 Prevalence of musculoskeletal disorders in clinical laboratory personnel in the city of Riobamba, Ecuador https://revistas.uautonoma.cl/index.php/ijmss/article/view/3025 <p>Introduction: Clinical laboratory personnel are exposed to multiple occupational hazards. However, most studies have focused on biological, physical and chemical risks, with little information on ergonomic risks and their relationship with musculoskeletal disorders (MSDs) in this population. Objective: To determine the prevalence of MSDs in clinical laboratory personnel in the city of Riobamba, Ecuador, and their association with personal and organizational factors. Methodology: Descriptive, observational, cross-sectional study conducted between June and November 2024. The Standardized Nordic Questionnaire to assess the presence of musculoskeletal symptoms in nine body regions: neck, shoulders, elbows, wrists/hands, upper back, lower back, hips/thighs, knees and ankles/feet, together with a survey on sociodemographic and organizational variables, was applied to 40 technicians and professionals from four private clinical laboratories in the city of Riobamba, Ecuador. A descriptive analysis was performed using absolute and relative frequencies, and Pearson’s Chi-square test was used to evaluate associations between variables. GraphPad Prism software version 8.0 was used, considering a value of p &lt; 0.05 as statistically significant. Results: 71.3 % of the participants reported musculoskeletal symptoms. The most affected body areas were the trunk (37.15 %), neck (15.33 %), shoulders (14.46 %) and wrists (10.02 %). The highest prevalence was observed in the age group 26 to 50 years. A significant association was found between the presence of MSDs and female sex (p = 0.007), as well as with shift work (p = 0.049). Conclusion: The results show a high prevalence of MSDs in clinical laboratory personnel, which highlights the need to implement preventive measures aimed at the ergonomic redesign of the work environment, as well as training programs focused on the specific risks associated with these functions.</p> Diego Tene Salcán Copyright (c) 2025 Diego Tene Salcán https://creativecommons.org/licenses/by/4.0 https://revistas.uautonoma.cl/index.php/ijmss/article/view/3025 Thu, 12 Jun 2025 00:00:00 +0000