Adherencia al tratamiento profiláctico en pacientes hemofílicos A severos

Abstract

A high adherence to prophylactic treatment in severe hemophilia patients increases and improves their quality of life. The lack of adherence to prophylactic treatment increases the chances of spontaneous hemorrhages and with them hemarthrosis and future arthropathies. Main objective: To analyze the current situation of adherence to prophylactic treatment in severe hemophilia A patients. Methodology: Our work consists of a bibliographical review of the scientific literature of the last 10 years on adherence to prophylactic treatment in severe hemophilia A patients. The search was conducted in different electronic databases. Results: Patients aged 0-12 years had the highest adherence, while lower adherence was detected in adolescent patients (13-18 years) and young adults (19-29 years). Main barriers: Patient denial of treatment, inability to understand benefits and interference with lifestyle. The evidence indicates a higher quality of life in patients with high adherence to prophylactic treatment. Conclusion: The adolescent population and the young adults present the highest risk of low adherence to prophylactic treatment, due to their transition from parental administration of the doses to the new self-infusion, due to the greater independence and freedom to decide for themselves about his illness.