Avances en el manejo de la sepsis: Nuevos aspectos terapéuticos
Contenido principal del artículo
Resumen
Citas
Ali, S. O., Yu, X. Q., Robbie, G. J., Wu, Y., Shoemaker, K., Yu, L., DiGiandomenico, A., Keller,
A. E., Anude, C., Hernandez-Illas, M., Bellamy, T., Falloon, J., Dubovsky, F., & Jafri, H. S. (2019). Phase 1 study of MEDI3902, an investigational anti–Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults. Clinical Microbiology and Infection, 25(5), 629.e1-629.e6. https://doi.org/10.1016/j.cmi.2018.08.004
Bracht, H., Hafner, S., & Weiß, M. (2019). Sepsis-Update : Definition und Epidemiologie Einführung Definition der Sepsis. Anästhesiologie Intensivmedizin Notfallmedizin Schmerztherapie, 54, 10–20.
Geven, C., Blet, A., Kox, M., Hartmann, O., Scigalla, P., Zimmermann, J., Marx, G., Laterre, P. F., Mebazaa, A., & Pickkers, P. (2019). A double-blind, placebo-controlled, randomised, multicentre, proof-of-concept and dose-finding phase II clinical trial to investigate the safety, tolerability and efficacy of adrecizumab in patients with septic shock and elevated adrenomedullin concentrat. BMJ Open, 9(2), 1–11. https://doi.org/10.1136/bmjopen-2018-024475
Ji, W., Meng, Y., Bo, L., Wan, X., & Deng, X. (2021). Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. In Chinese Journal of Anesthesiology (Vol. 41, Issue 12). https://doi.org/10.3760/cma.j.cn131073.20211210.01201
Laterre, P. F., Berry, S. M., Blemings, A., Carlsen, J. E., François, B., Graves, T., Jacobsen, K., Lewis, R. J., Opal, S. M., Perner, A., Pickkers, P., Russell, J. A., Windeløv, N. A., Yealy, D. M., Asfar, P., Bestle, M. H., Muller, G., Bruel, C., Brulé, N., … Angus, D. C. (2019). Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients with Septic Shock: The SEPSIS-ACT Randomized Clinical Trial. JAMA - Journal of the American Medical Association, 322(15), 1476–1485. https://doi.org/10.1001/jama.2019.14607
Nakashima, M., Kanamaru, M., Umemura, K., & Tsuruta, K. (1998). Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers. Journal of Clinical Pharmacology, 38(1), 40–44. https://doi.org/10.1002/j.1552-4604.1998.tb04375.x
Pickkers, P., Heemskerk, S., Schouten, J., Laterre, P. F., Vincent, J. L., Beishuizen, A., Jorens, P. G., Spapen, H., Bulitta, M., Peters, W. H. M., & van der Hoeven, J. G. (2012). Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: A prospective randomized double-blind placebo-controlled trial. Critical Care, 16(1), R14. https://doi.org/10.1186/cc11159
Vincent, J. L., Ramesh, M. K., Ernest, D., Larosa, S. P., Pachl, J., Aikawa, N., Hoste, E., Levy, H., Hirman, J., Levi, M., Daga, M., Kutsogiannis, D. J., Crowther, M., Bernard, G. R., Devriendt, J., Puigserver, J. V., Blanzaco, D. U., Esmon, C. T., Parrillo, J. E., … Kaul, I. (2013). A randomized, double-blind, placebo-controlled, phase 2b Study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation. Critical Care Medicine, 41(9), 2069–2079. https://doi.org/10.1097/CCM.0b013e31828e9b03
Xiang-Qing Yu, G. J. R., Yuling Wu, M. T. E., Jensen, K., Schwartz, H. I., Terramika Bellamy, a M. H.-I., & Jafria, H. S. (2017). Safety, Tolerability, and Pharmacokinetics of MEDI4893, an Investigational, Extended-Half-Life, Anti-Staphylococcus aureus Alpha-Toxin Human Monoclonal Antibody, in Healthy Adults. Antimicrobial Agents and Chemotherapy, 61(1), 1–9. doi: https://doi.org/10.1128/AAC.01020-16