Surgical peripheral lymph node biopsies in Makurdi, Nigeria.

Article Sidebar

PDF
Published: Sep 1, 2019
DOI: https://doi.org/10.32457/ijmss.2019.024
Keywords:
Surgical lymph node biopsy, lymph node enlargement

Article Details

How to Cite
Eke, B., Ojo, B., Vhriterhire, R., Akper, I., Ugwu, V., & Udu, C. (2019). Surgical peripheral lymph node biopsies in Makurdi, Nigeria. International Journal of Medical and Surgical Sciences, 6(3), 75–78. https://doi.org/10.32457/ijmss.2019.024
Issue
Vol. 6 No. 3 (2019): September 2019
Section
Research Article

The publication is free and its contents are distributed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND 4.0). The rights of the works published in this journal are property of the author and they are free to distribute and disseminate the same sources as long as he correctly cites the font of publication, these acts are not for commercial purposes and no derivative works are generated.

Surgical peripheral lymph node biopsies in Makurdi, Nigeria.

Main Article Content

Barnabas Eke
Benue State University, Makurdi, Nigeria
Babarinde Ojo
Benue State University, Makurdi, Nigeria
Rymond Vhriterhire
Benue State University, Makurdi, Nigeria
Issac Akper
Benue State University, Makurdi, Nigeria
Victor Ugwu
National Orthopedic Hospital, Enugu, Nigeria
Confort Udu
General Hospital, North Bank, Makurdi, Nigeria

Abstract

This study aims at determining the diagnostic value of peripheral lymph node biopsy and common causes of lymph node enlargement from biopsies obtained from patients with lymph-node enlargement at different sites in a teaching hospital in north central Nigeria town of Makurdi, Benue State. This is a retrospective study of surgical peripheral lymph node biopsies received in the department of Anatomic Pathology, Benue State University Teaching Hospital, Makurdi, Nigeria from February, 2012 to September, 2019. Total number of lymph node biopsies during the period was 47 representing 1.0% of surgical pathology specimens submitted to the department; 25 cases were females and 22 were males. Metastatic nodal involvement (57%), lymphoma (23%) and tuberculosis lymphadenitis (11%) were the most common causes of lymph node enlargement. All the studied nodes were localized. The most common sites of lymphadenopathy were axillary (21%), cervical (16%) and Inguinal (6%). While axillary lymph node enlargements were mostly associated with tumor metastasis, cervical and inguinal node enlargements were mostly associated with tuberculosis and lymphoma, respectively. Surgical excision of nodal enlargement for histological examination represents a simple, good diagnostic yield with lack of significant morbidity or mortality.

References

Aftab K, Umar B. Giant cell tumor of bone with lymph node metastasis: A rare presentation. Indian J Pathol Microbiol. 2011; 54(2) 396-397.

Allhiser JN, Mcknight TA, Shank JC. Lymphadenopathy in a family practice J Fam Pract. 1981; 12(1):27-32.

Anunobi CC, Banjo AA, Abdulkareem FB, Daramola AO, Abudu EK. Review of the histopathologic patterns of superficial lymph node diseases, in Lagos (1991-2994). Niger Postgrad Med J. 2008; 15(4): 243-6.

Cotran RS, Kumar V, Collins T. Pathological Basis of Diseases. 6th ed. Philadelphia: W.B Saunders and company; 1999.

Ferrer R. “Lymphadenopathy: differential diagnosis and evaluation”. Am Fam Physician 1998; 58(6): 1313-1320.

Gamberi G, Serra M, Ragazzini P, Magagnoli G, Pazzaglia L, Ponticelli F, Ferrari C, Zanasi M, Bertoni F, Picci P, Benassi M. Identification of markers of possible prognostic value in 57 giant cell tumor of bone. Oncol Rep. 2003; 10(2): 351-6.

Getachew A, Demissie M, Gemechu T. Pattern of histopathologic diagnosis of lymph node biopsies in a teaching hospital in Addis Ababa, 1981-1990 GC. Ethiop Med J. 1999; 37(2): 121-7.

Ghirardelli ML, Jemos V, Gobbi PG. Diagnostic approach to lymph node enlargement. Haematologica. 1999; 84(3); 242-247.

Jaffe ES, Harris NL, Stein H, Isaacson PJ. Classification of lymphoid neoplasms: the microscope as a tool for disease discovery. Blood. 2008; 112(12):4384-99.

Kunitz G. An approach to peripheral lymphadenopathy in adult patients. West J Med. 1985; 143(3):393-396.

Libman H. Generalized lymphadenopathy. J Gen Intern Med. 1987;2(1):48-58.

Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A. Peripheral lymphadenopathy: Approach and diagnostic tools. Iran J Med Sci. 2014; 39(2): 158-170.

Moorland B. Lymphadenopathy. Arch Dis Child. 1995; 73:476-9.

Obafunwa JO, Olomu IN, Onyia NJ. Primary peripheral lymphadenopathy in Jos, Nigeria. West Afr J. Med. 1992; 11(1):25-28.

Ochicha O, Edino ST, Mohammed AZ, Umar AB, Atanda AT. Pathology of peripheral lymph node biopsies in Kane, northern Nigeria. Ann Afr Med. 2007; 6(3):104-8.

Ojo BA, Buhari MO. Malani SA, Abdulrahaman MB. Surgical lymph node biopsies in University of Ilorin Teaching Hospital, Ilorin, Nigeria. Niger Postgrad Med J. 2005, 12(4):299-304.

Okolo SN, Nwana EJ. Mohammed AZ. Histopathologic diagnoses of lymphadenopathy in children in Jos, Nigeria. Niger Postgrad Med J. 2003: 10(3): 165-7.

Shrestha AL, Shrestha P. Peripheral lymph node excisional biopsy: yield relevance and outcomes in a remote surgical setup. Surg Res Pract. 2018; 8120390.

Tiwari M, Aryal G, Shrestha R, Rauniyar SK, Shrestha HG. Histopathologic diagnosis of lymph node biopsies. Nepal Med Coll J. 2007; 9(4) 259-61.

Vassall A, Mustapha G. Copenhagen Consensus Center. Nigeria perspective: Tuberculosis. 2015. Available at https://www.copenhagenconsensus.com/sites/default/files/nigeria_tb_resource_packet_0.pdf.

Williamson HA Jr. Lymphadenopathy in a family practice, a descriptive study of 249 cases. J Fam Pract. 1985; 20(5):449-452.

World Health Organization. Fact sheets. Tuberculosis. 2018. Available at htpp:-who.int/news-room/fact-sheet/2018.