Complex organic molecules, from astronomy to biochemistry

Complex organic molecules, from astronomy to biochemistry

Main Article Content

Abraham Urzúa Castro

Abstract

To date, about 250 molecules have been discovered in the interstellar medium or circumstellar shells, many of these are complex organic molecules (COMs). The region where a large part of these molecules have been discovered is the molecular cloud of Sagittarius B2 (Sgr B2), the region richest in molecules in Milky Way. Molecules of different types such as molecular ions, radicals, ring molecules and stable molecules have been detected. Some of these are formed by gas phase chemistry and others on the surface of interstellar dust grains. The detection of these molecules has been achieved by radiotelescopes at millimeter and submillimeter wavelengths. Several molecules of biological interest have been detected as precursors of sugars, nucleobases, aminoacids, phospholipids and even a chiral molecule. The discovery of complex organic molecules in space not only contributes to understanding the chemical composition and evolution of the universe, but also supports the hypothesis of "exogenous delivery" at the origin of life.

References

Belloche, A., R. T. Garrod, H. S.P. Müller, K. M. Menten, C. Comito, and P. Schilke. 2009. “Increased Complexity in Interstellar Chemistry: Detection and Chemical Modeling of Ethyl Formate and n-Propyl Cyanide in Sagittarius B2(N)”. Astronomy and Astrophysics 499 (1): 215–32. https://doi.org/10.1051/0004-6361/200811550

Catalog [CDMS Classic Documentation]. Accessed May 19, 2021. https://cdms.astro.uni-koeln.de/classic/.

Cernicharo, José, Ana M. Heras, A. G. G. M. Tielens, Juan R. Pardo, Fabrice Herpin, Michel Guélin, and L. B. F. M. Waters. 2001. “Infrared Space Observatory’s Discovery of C4H2, C6H2, and Benzene in CRL 618”. The Astrophysical Journal 546 (2): L123–26. https://doi.org/10.1086/318871

Groen, Joost, David W. Deamer, Alexander Kros, and Pascale Ehrenfreund. 2012. “Polycyclic Aromatic Hydrocarbons as Plausible Prebiotic Membrane Components”. Origins of Life and Evolution of Biospheres 42 (4): 295–306. https://doi.org/10.1007/s11084-012-9292-3

Jiao, He, Francis E. Toriello, Shahnewaz M. Emtiaz, Thomas Henning, and Gianfranco Vidali. 2021. “Phase Transition of Interstellar CO Ice”. The Astrophysical Journal Letters 915 (1): L 23. https://doi.org/10.3847/2041-8213/AC0A7C

Herbst, Eric, and Ewine F. Van Dishoeck. 2009. “Complex Organic Interstellar Molecules”. Annual Review of Astronomy and Astrophysics 47: 427–80. https://doi.org/10.1146/annurev-astro-082708-101654

Hollis, J. M., F. J. Lovas, and P. R. Jewell. 2000. “Interstellar Glycolaldehyde: The First Sugar”. The Astrophysical Journal 540 (2): L107–10. https://doi.org/10.1086/312881

Irvine, William M. 2011. “Molecular Cloud”. In Encyclopedia of Astrobiology, 1070–1070. Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-11274-4_1010

Jørgensen, Jes K., Cécile Favre, Suzanne E. Bisschop, Tyler L. Bourke, Ewine F. Van Dishoeck, and Markus Schmalzl. 2012. “Detection of the Simplest Sugar, Glycolaldehyde, in a Solar-Type Protostar with ALMA”. Astrophysical Journal Letters 757 (1): 4. https://doi.org/10.1088/2041-8205/757/1/L4

Kaur, Sarabjeet, Ashita Ohri, and Purshotam Sharma. 2019. “Could Purines Be Formed from Cyanamide and Cyanoacetylene in a Prebiotic Earth Environment?”. ACS Omega 4 (7): 12771–81. https://doi.org/10.1021/acsomega.9b01169

McCollom, Thomas M. 2013. “Miller-Urey and beyond: What Have We Learned about Prebiotic Organic Synthesis Reactions in the Past 60 Years?”. Annual Review of Earth and Planetary Sciences 41 (May): 207–29. https://doi.org/10.1146/annurev-earth-040610-133457

McGuire, Brett A., P. Brandon Carroll, Ryan A. Loomis, Ian A. Finneran, Philip R. Jewell, Anthony J. Remijan, and Geoffrey A. Blake. 2016. “Discovery of the Interstellar Chiral Molecule Propylene Oxide (CH3CHCH2O)”. Science 352 (6292): 1449–52. https://doi.org/10.1126/science.aae0328

McGuire, Brett A. 2018. “2018 Census of Interstellar, Circumstellar, Extragalactic, Protoplanetary Disk, and Exoplanetary Molecules”. The Astrophysical Journal Supplement Series 239: 17. https://doi.org/10.3847/1538-4365/aae5d2

Menten, K M, C Comito, H S P Müller, P Schilke, J Ott, S Thorwirth, and C Hieret. 2008. “Astrophysics Detection of Amino Acetonitrile in Sgr B2(N)”. A&A 482: 179–96. https://doi.org/10.1051/0004-6361:20079203

Oba, Yasuhiro, Yoshinori Takano, Hiroshi Naraoka, Naoki Watanabe, and Akira Kouchi. 2019. “Nucleobase Synthesis in Interstellar Ices”. https://doi.org/10.1038/s41467-019-12404-1

Ohishi, Masatoshi. 2016. “Search for Complex Organic Molecules in Space”. Journal of Physics: Conference Series 728 (5). https://doi.org/10.1088/1742-6596/728/5/052002

Ohishi, Masatoshi. 2019. “Prebiotic Complex Organic Molecules in Space”. Astrobiology: From the Origins of Life to the Search for Extraterrestrial Intelligence, 11–21. https://doi.org/10.1007/978-981-13-3639-3_2

Oka, Takeshi. 2006. “Interstellar H3+”. Proceedings of the National Academy of Sciences of the United States of America. National Academy of Sciences. https://doi.org/10.1073/pnas.0601242103

Platts, Simon Nicholas. 2006. “The ‘PAH World’: Discotic Polynuclear Aromatic Compounds as Mesophase Scaffolding at the Origin of Life”. https://nla.gov.au/nla.cat-vn4225103

Rivilla, Víctor M, Izaskun Jiménez, Jim´ Jiménez-Serra, Jesús Jes´, Jesús Martín-Pintado, Carlos Briones, Lucas F Rodríguez-Almeida, et al. 2021. “Discovery in Space of Ethanolamine, the Simplest Phospholipid Head Group”. https://doi.org/10.1073/pnas.2101314118

Sandford, Scott A., Michel Nuevo, Michel Nuevo, Partha P. Bera, Partha P. Bera, and Timothy J. Lee. 2020. “Prebiotic Astrochemistry and the Formation of Molecules of Astrobiological Interest in Interstellar Clouds and Protostellar Disks”. Chemical Reviews 120 (11): 4616–59. https://doi.org/10.1021/acs.chemrev.9b00560

Sewilo, Marta, Remy Indebetouw, Steven B. Charnley, Sarolta Zahorecz, Joana M. Oliveira, Jacco Th van Loon, Jacob L. Ward, et al. 2018. “The Detection of Hot Cores and Complex Organic Molecules in the Large Magellanic Cloud”. ArXiv. arXiv. https://doi.org/10.3847/2041-8213/aaa079

Snell, Ronald L. 2011. “Interstellar Medium”. In Encyclopedia of Astrobiology, 837–43. Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-11274-4_801

Whittet, Douglas. 2011. “Interstellar Dust”. In Encyclopedia of Astrobiology, 832–35. Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-11274-4_799