Gastroesophageal Reflux Disease
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Resumen
Gastroesophageal reflux disease (GERD) is one of the most frequent causes of consultation in primary care and gastroenterology. Over 40 % of the general population experiences occasional heartburn and regurgitation due to GERD. It is a complex disease and physiology and pathogenesis are not yet completely defined. However, abnormalities in the lower esophageal sphincter, esophageal motility or gastric emptying can cause or worsen GERD. There are various diagnostic and therapeutic approaches; however, the use of proton-pump inhibitor fundoplication permanence and (antireflux surgery), are the most effective options.
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American College of Gastroenterology (ACG). Web Site. 2016. Disponible en: http://www.acg.gi.org/ acg-dev/staging/members/guides/gerdabs.html.
Armstrong, D.; Marshall, J. K.; Chiba, N.; Enns, R.; Fallone,C. A.; Fass, R.; Hollingworth, R.; Hunt, R. H.; Kahrilas, P. J.; Mayrand, S.; Moayyedi, P.; Paterson, W. G.; Sadowski, D.; van Zanten, S. J. & Canadian Association of GastroenterologyGERD Consensus Group. Canadian Consensus Conference on the management of gastroesophageal reflux disease in adults - update 2004.
Can. J. Gastroenterol., 19(1):15-35, 2005.
Asociación Española de Gastroenterología (AEG). Guía de Práctica Clínica. Web Site. 2016. Disponible en: http://www.aegastro.es/docentia/atencion-primaria/guias-practica-clinica
Avidan, B.; Sonnenberg, A.; Giblovich, H. & Sontag,S. J. Reflux symptoms are associated with psychiatric disease. Aliment. Pharmacol. Ther., 15(12):1907-12, 2001.
Cameron, A. J.; Lagergren, J.; Henriksson, C.; Nyren, O.; Locke, G. R. 3rd. & Pedersen, N. L. Gastroesophageal reflux disease in monozygotic and dizygotic twins. Gastroenterology, 122(1):55-9, 2002.
Cohen, H.; Moraes-Filho, J. P.; Cafferata, M. L.; Tomasso, G.; Salis, G.; González, O.; Valenzuela, J.; Sharma, P.; Malfertheiner, P.; Armstrong, D.; Lundell, L.; Corti, R.; Sakai, P.; Ceconello, I. & Latin-American GORD Consensus Group. Latin-American GORD Consensus Group. An evidence-based, LatinAmerican consensus on gastro-oesophageal reflux disease. Eur. J. Gastroenterol. Hepatol., 18(4):349-68, 2006.
Collings, K. L.; Pierce Pratt, F.; Rodriguez-Stanley, S.; Bemben, M. & Miner, P. B. Esophageal reflux in conditioned runners, cyclists, and weightlifters. Med. Sci. Sports Exerc., 35(5):730-5, 2003.
Chrysos, E.; Athanasakis, E.; Pechlivanides, G.; Tzortzinis, A.; Mantides, A. & Xynos, E. The effect of total and anterior partial fundoplication on antireflux mechanisms of the gastroesophageal junction. Am. J. Surg., 188(1):39-44, 2004.
Dore, M. P.; Pedroni, A.; Pes, G. M.; Maragkoudakis,E.; Tadeu, V.; Pirina, P.; Realdi, G.; Delitala, G. & Malaty, H. M. Effect of antisecretory therapy on atypical symptoms in gastroesophageal reflux disease. Dig. Dis. Sci.,52(2):463-8, 2007.
Draaisma, W. A.; Rijnhart-de Jong, H. G.; Broeders, I. A.; Smout, A. J.; Furnee, E. J. & Gooszen, H. G. Five-year subjective and objective results of laparoscopic and conventional Nissen fundoplication: a randomized trial. Ann. Surg., 244(1):34-41, 2006.
Engström, C.; Ruth, M.; Lönroth, H. & Lundell, L. Manometric characteristics of the gastroesophageal junction after anterior versus posterior partial fundoplication. Dis. Esophagus, 18(1):31-6, 2005.
Galindo, G.; Vassalle, J.; Marcus, S. N. & Triadafilopoulos, G. Multimodality evaluation of patients with gastroesophageal reflux disease symptoms who have failed empiric proton pump inhibitor therapy. Dis. Esophagus, 26(5):443-50, 2013.
Garg, S. K. & Gurusamy, K. S. Laparoscopic fundoplication surgery versus medical management for gastro-oesophageal reflux disease (GORD) in adults. Cochrane Database Syst. Rev., 11:CD003243, 2015
Fass, R.; Achem, S. R.; Harding, S.; Mittal, R. K. & Quigley, E. Review article: supra-oesophageal manifestations of gastro-oesophageal reflux disease and the role of night-time gastrooesophageal reflux. Aliment. Pharmacol. Ther., 20 Suppl. 9:26-38, 2004.
Gatta, L.; Vaira, D.; Sorrenti, G.; Zucchini, S.; Sama, C. & Vakil, N. Meta-analysis: the efficacy of proton pump inhibitors for laryngeal symptoms attributed to gastro-oesophageal reflux disease. Aliment. Pharmacol. Ther., 25(4):385-92, 2007.
Glatzel, D.; Abdel-Qader, M.; Gatz, G. & Pfaffenberger, B. Pantoprazole 40 mg is as effective as esomeprazole 40 mg to relieve symptoms of gastroesophageal reflux disease after 4 weeks of treatment and superior regarding the prevention of symptomatic relapse. Digestion, 75 Suppl. 1:69-78, 2007.
Håkanson, B. S.; Thor, K.B.; Thorell, A. & Ljungqvist, O. Open vs laparoscopic partial posterior fundoplication. A prospective randomized trial. Surg. Endosc., 21(2):289-98, 2007.
Harding, S. M. Gastroesophageal reflux: a potential asthma trigger. Immunol. Allergy Clin. North Am., 25(1):131-48, 2005.
Hawkey, C. J.; Jones, R. H.; Yeomans, N. D.; Scheiman, J. M.; Talley, N. J.; Goldstein, J. L.; Ahlbom, H. & Naesdal, J. Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs. Aliment. Pharmacol. Ther., 25(7):813-21, 2007.
Kahrilas, P. J.; Miner, P.; Johanson, J.; Mao, L.; Jokubaitis, L. & Sloan, S. Efficacy of rabeprazole in the treatment of symptomatic gastroesophageal reflux disease. Dig. Dis. Sci., 50(11):2009-18, 2005.
Kim, J.; Ogai, A.; Nakatani, S.; Hashimura, K.; Kanzaki, H.; Komamura, K.; Asakura, M.; Asanuma, H.; Kitamura, S.; Tomoike, H. & Kitakaze, M. Impact of blockade of histamine H2 receptors on chronic heart failure revealed by retrospective and prospective randomized studies. J. Am. Coll. Cardiol., 48(7):1378-84,2006.
Lundell, L.; Bell, M. & Ruth, M. Systematic review:Laparoscopic fundoplication for gastroesophageal reflux disease in partial responders to proton pump inhibitors. World J.Gastroenterol., 20(3):804-13, 2014.
Manterola, C.; Calderón, C.; Pérez, O.; Flores, P. & Hofmann, E. Esofagitis por reflujo gastroesofágico y alteración de párametros presivos esofágico.Acta Méd. Colomb., 23(1):7-14, 1998.
Manterola, C.; Muñoz, S.; Flores, P.; Fernández, E. & Capurro, M. Study of association between the magnitude of sphincter hypotonia and esophageal motor disorders. Rev. Med. Chil., 128(7):721-8,2000.
Manterola Delgado, C.; Gutiérrez Luengo, R.; Soto F., A.; Cuadra M., A.; Maurer D., J.; Moreno L., F. & Leiva M., M. Modificación de variables clínicas y del laboratorio en pacientes sometidos a cirugía antirreflujo. Rev. Chil. Cir., 53(3):287-92,2001a.
Manterola, C.; Muñoz, S.; Fernández, E. & Flores, P. Estudio de asociación entre esofagitis endoscópica y deterioro de parámetros motores esofágicos en pacientes con enfermedad por reflujo gastroesofágico. Rev. Chil. Cir., 53(4):362-9, 2001b.
Manterola, C.; Muñoz, S.; Grande, L. & Bustos, L. Initial validation of a questionnaire for detecting gastroesophageal reflux disease in epidemiological settings. J. Clin. Epidemiol.,55(10):1041-5, 2002.
Manterola, C.; Barroso, M. S.; Losada, H.; Muñoz, S. & Vial, M. Prevalence of esophageal disorders in patients with recurrent chest pain. Dis. Esophagus, 17(4):285-91, 2004.
Manterola D., C.; Bustos M., l. & Vial G., M. Prevalencia de enfermedad por reflujo gastroesofágico en población general urbana adulta. Rev. Chil. Cir., 57(6):476-82, 2005.
Miner, P. Jr.; Katz, P. O.; Chen, Y. & Sostek, M. Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study. Am. J. Gastroenterol., 98(12):2616-20, 2003.
Nocon, M.; Labenz, J.; Jaspersen, D.; MeyerSabellek, W.; Stolte, M.; Lind, T.; Malfertheiner, P. & Willich, S. N. Association of body mass index with heartburn, regurgitation and esophagitis: results of the Progression of Gastroesophageal Reflux Disease study. J. Gastroenterol. Hepatol., 22(11):1728-31, 2007.
Pessaux, P.; Arnaud, J. P.; Delattre, J. F.; Meyer, C.; Baulieux, J. & Mosnier, H. Laparoscopic antireflux surgery: five-year results and beyond in 1340 patients. Arch. Surg., 140(10):946-51, 2005.
Salminen, P. T.; Hiekkanen, H. I.; Rantala, A. P. & Ovaska, J. T. Comparison of long-term outcome of laparoscopic and conventional nissen fundoplication: a prospective randomized study with an 11-year follow-up. Ann. Surg., 246(2):201-6, 2007.
Scholten, T.; Teutsch, I.; Bohuschke, M. & Gatz, G. Pantoprazole on-demand effectively treats symptoms in patients with gastro-oesophageal reflux disease. Clin. Drug Investig., 27(4):287-96, 2007.
Sigterman, K. E.; van Pinxteren, B.; Bonis, P. A.; Lau, J. & Numans, M. E. Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastrooesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst. Rev., 5:CD002095, 2013.
Vcev, A.; Begic, I.; Ostojic, R.; Jurcic, D.; Bozic, D.; Soldo, I.; Gmajnic, R.; Kondza, G.; Khaznadar, E. & Micunovic, N. Esomeprazole versus pantoprazole for healing erosive oesophagitis. Coll. Antropol., 30(3):519-22, 2006.