Oral cavity cancer in patients from the department of head and neck surgery – chair and otorhinolaryngology service of the Hospital de Clínicas – National University of Asunción

Oral cavity cancer in patients from the department of head and neck surgery – chair and otorhinolaryngology service of the Hospital de Clínicas – National University of Asunción

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Evelio Legal Balmaceda
Marta Osorio Fleitas
José Ortiz Bogado
Carlos Mena Canata
Raúl Andrés Tornaco Maidana


Introduction: The oral cavity is continuously exposed to inhaled and ingested carcinogens (mainly tobacco and alcohol), and therefore it is the most common site for the origin of neoplasms in the head and neck region. Methods: A descriptive, retrospective, observational study of non-probabilistic sampling of consecutive cases was carried out. Adult patients with a clinical and pathological diagnosis of oral cavity cancer were included. Results: A series of 17 cases of oral squamous cell carcinoma was included, 13 men (76%) and 4 women (24%). The age of the individuals ranged between 32 and 73 years. 65% of the patients were smokers, and 71% reported consumption of alcoholic beverages. The tongue was the most frequent tumor location, 71% were in stage IV, and with a moderate degree of histological differentiation. Conclusion: Most of the patients in this study were males between 50 and 70 years of age. A high percentage of patients reported smoking, and an even higher percentage of alcohol consumption. The most frequently affected subsite is the tongue, in advanced stages and a moderate degree of differentiation.


Abu-Ghanem S., Yehuda, M., Carmel, N., Leshno, M., Abergel, A., Gutfeld, O. & Fliss, D. (2016) Elective Neck Dissection vs Observation in Early-Stage Squamous Cell Carcinoma of the Oral Tongue with No Clinically Apparent Lymph Node Metastasis in the Neck: A

Systematic Review and Meta-analysi. JAMA Otolaryngol Head Neck Surg, 142(9), 857-865. https://doi.org/10.1001/jamaoto.2016.1281

Alonso, J., Kuan, E., Arshi, A. & St. John, M. (2018) A population-based analysis of verrucous carcinoma of the oral cavity. Laryngoscope, 128(2), 393-397. https://doi.org/10.1002/lary.26745

Cannon, R., Sowder, J., Buchmann, L., Hun, J., Hitchcock, Y., Lloyd, S., Grossman, K. & Monroe, M. (2017) Increasing use of nonsurgical therapy in advanced-stage oral cavity cancer: A population-based study. Head Neck, 39(1), 82-91. https://doi.org/10.1002/hed.24542

Cooper, J., Porter K., Mallin K., Hoffman H., Weber, R., Ang K., Gay E. & Langer, C. (2009) National Cancer Database report on cancer of the head and neck: 10-year update. Head Neck, 31(6), 748-758. https://doi.org/10.1002/hed.21022

Dedivitis, R., França, C., Mafra A., Guimarães, F. y Guimarães A. (2004) Características clínico-epidemiológicas no carcinoma espinocelular de boca e orofaringe. Rev Bras Otorrinolaringol, 70(1), 35-40. https://doi.org/10.1590/S0034-72992004000100006

De Oliveira, S., do Nascimento, M. & Vamondes, M. (2022) Malignant neoplasms of the oral cavity and oropharynx treated in Brazil: what do hospital cancer records reveal? Brazilian Journal of Otorhinolaryngology, 88(2), 168-173. https://doi.org/10.1016/j.bjorl.2020.05.019

Global cancer observatory (Globocan) (s.f.). Disponible en: https://gco.iarc.fr Lydiatt, W, Patel, S., O’Sullivan, B., Brandwein, M., Ridge, J., Miggliacci, J., Loomis, a. & Shah, J. (2017) Head and neck cancers-major changes in the American Joint Committee on cancer eighth edition cancer staging manual. CA: A Cancer Journal for Clinicians, 67(2),122-37. https://doi.org/10.3322/caac.21389

Maxwell, J., Thompson, L., Brandwein-Gensler, M., Weiss, B., Canis, M., Purgina, B., Prabhu, A., Lai, C., Shuai, Y., Carroll, W., Morlandt, A., Duvvuri, U., Kim, S., Johnson, J., Ferris, R., Seethala, R. & Chiosea, S. (2015) Early Oral Tongue Squamous Cell Carcinoma Sampling of Margins from Tumor Bed and Worse Local Control. JAMA Otolaryngol Head Neck Surg, 141(12), 1104-1110. https://doi.org/10.1001/jamaoto.2015.135

Nyi Nyi, M., Gibson, T., Hanchard, B., Waugh, N. & McNaughton, N. (2014) Trends in Incidence and Age Distribution of Oral Cavity and Oropharyngeal Squamous Cell Carcinomas, Kingston and St Andrew, Jamaica, 1987-2007. West Indian Med J, 63(2): 128-133. https://doi.org/10.7727/wimj.2013.164

Romagna, D., Moura de Oliveira, M., Guimarães, L., Stein, C., Neves, F., Texeira, R., Carvalho, D., Naghavi, M. & Pinto, B. (2022) Incidence and mortality rates of lip, oral cavity, and pharynx cancers in Brazil: time-trend and age-period-cohort analysis from the

last 30 years, Global Burden of Disease Study. Revista da Sociedade Brasileira de Medicina Tropical, 55(1). https://doi.org/10.1590/0037-8682-0286-2021

Sowder, J., Cannon, R., Buchmann, L., Hunt, J., Hitchcock, Y., Lloyd, S., Grossmann, K. & Monroe, M. (2017) Treatment-related determinants of survival in early-stage (T1- 2N0M0) oral cavity cancer: A population-based study. Head Neck, 39(5), 876-880.


Zacarías Yunis, A. (2017) Prevalencia de cáncer oral en el Instituto Nacional del Cáncer de Paraguay, de los años 2009 al 2013. Disponible en: http://investigacion.uninorte.edu.py/rev-uninorte-med-2017-02/